Practical advice

Testosterone therapy confers a wide range of health benefits for hypogonadal men, including improvements in body composition (reduction in body fat, increase in muscle mass, weight loss), lipid profile, cardiovascular function, insulin sensitivity/glucose metabolism, bone mineral density, inflammatory parameters, quality of life and increased longevity.1,2

Despite this, many men fail to achieve these treatment benefits simply because they stop treatment or do not adhere to the treatment. This can easily be prevented by informing patients about all benefits they have to gain is they adhere to their testosterone treatment, as well as how soon they can expect to notice the different health benefits.

This interactive tool gives a graphical visualization of when to expect onset of improvements as well as maximal improvements.

Link to tool

For more information, see our editorials:

Time-course of biological effects of testosterone replacement therapy

Adherence to testosterone therapy - short term treatment is not sufficient for achievement of maximal benefits

Long-term testosterone treatment with different testosterone preparations - provocative results on diagnosis and adherence


Long term therapy with Nebido®

Information resources


  1. Saad F, Aversa A, Isidori AM, et al. Onset of effects of testosterone treatment and time span until maximum effects are achieved. Eur J Endocrinol 2011;165(5):675-685.
  2. Traish AM. Outcomes of testosterone therapy in men with testosterone deficiency (TD): Part II. Steroids. 2014;88C:117-126.
  • PP-NEB-ALL-0347-1

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Page last modified Mon, 16/09/2019

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