STUDY: Haider KS, Haider A, Doros G, Traish A. Long-Term Testosterone Therapy Improves Urinary and Sexual Function, and Quality of Life in Men with Hypogonadism: Results from a Propensity Matched Subgroup of a Controlled Registry Study. J Urol. 2018;199(1):257-265.
It is well documented that hypogonadism (testosterone deficiency) is associated with obesity, metabolic syndrome, reduced libido, erectile dysfunction and orgasmic dysfunction, and that testosterone therapy in these men improves cardiometabolic and sexual function.
However, concern remains that testosterone therapy may worsen lower urinary tract symptoms (LUTS) by possibly causing benign prostatic hyperplasia (BPH), although few major adverse events have been reported.